Séminaire du Lundi ce mardi 26 mai | Josefa Gonzalez

Mardi 26 Mai, après un nouveau long weekend aura lieu un séminaire exceptionnel en remplacement du séminaire du lundi!

Josefa Gonzalez de l’Institut de Biologie Évolutive de Barcelone, invitée de l’équipe « Évolution, Vecteurs, Adaptation et Symbiose », viendra nous présenter ses travaux de recherche portant sur les éléments transposables et leur rôle dans l’adaptation des génomes.

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Transposable elements and adaptive evolution in Drosophila

Josefa González
Institute of Evolutionary Biology (CSIC-UPF). Barcelona, Spain

Transposable elements are likely to play a role in adaptive evolution because they are powerful mutagens that create a great variety of mutations. However, the role of transposable elements in adaptation has been understudied due to methodological limitations. Next-generation sequencing technologies allow us to study transposable-element-induced adaptations to an unprecedented scale.

We have performed a genome-wide screening looking for transposable element-induced adaptations in the model species Drosophila melanogaster. We have identified 41 insertions likely to play a role in adaptation to the out-of-Africa environments. 25 of these 41 putatively adaptive transposable elements show signatures of selection at the DNA level. Furthermore, we have been able to map four of these transposable element insertions to their ecologically relevant phenotypic effect and to unravel the molecular mechanism behind them. Our results suggest that transposable elements play an important role in stress-response pathways. Our results also showed the variety of molecular mechanisms by which transposable element affect gene regulation: from adding transcription factor binding sites to changing the 3’UTR lenght.
Josefa lab website: www.biologiaevolutiva.org/gonzalez_lab

Notez le dans vos agendas: rdv a 14h, salle louis Thaler, bat 22, 2eme etage, UM, ISEM.

A Mardi prochain,
Anna

Séminaire du Lundi 11 mai 205 | François Rousset

Séminaire du Lundi,  François Rousset nous parle de:

Some new tools for analysing spatial data, and perhaps an alternative to Approximate Bayesian Computation.

Son exposé sera en français et les diapos en anglais.
Venez nombreux l’écouter à 11h salle Louis Thaler, bat 22, 2e étage, UM, ISEM.

A lundi!

suit son résumé:
Various statistical methods have been proposed for analysis of spatial data, applicable for e.g. assessment of genotype-environment correlation or presence/absence distributional data. These typically suffer from a number of problems ranging from being basically wrong to being poorly implemented. I will describe a new implementation of methods to fit spatial mixed models, that addresses these concerns. I will then outline how some of these methods could be used for the quite distinct problem of inference from simulated distributions of summary statistics, and could therefore provide an alternative to approximate Bayesian computation (ABC). This alternative would be able to provide better confidence intervals than ABC may provide.

manifestation nationale « Les Rendez-vous aux jardins »

affiche-rvjDans le cadre de la manifestation nationale « Les Rendez-vous aux jardins », vous trouverez ci-joint l’annonce d’une conférence grand public :

http://www.cassinomagus.fr/agenda/saison-2015-agenda/rencontre-archeologique-avec-phlippe-poirier.html

Philippe Poirier est archéologue à l’ISEM  dans l’équipe « Dynamique de la Biodiversité et Anthropoécologie » dirigée par Jean-François Terral
complément :cadre de la manifestation :
http://rendezvousauxjardins.culturecommunication.gouv.fr/