<< Vers l'annuaire

Mathieu Sicard

Professeur Equipe Evolution, Vecteurs, Adaptation et Symbioses
Emailmathieu.sicard@univ-montp2.fr
Tél. +33 (0)4 67 14 32 89
Localisation bâtiment 22, étage 1
Mots clés Symbiose Co-évolution Immunité innée Parasitisme Microbiologie Pathogènes

Le fil conducteur de mes recherches est l’étude de la co-évolution au sein des symbioses entre eucaryotes et procaryotes en évaluant les conséquences de ces interactions durables sur les traits d’histoire de vie des partenaires notamment sur le système immunitaire hôte.

En ce moment, j’étudie plus particulièrement les différents patrons d’incompatibilité cytoplasmique induits par Wolbachia chez les moustiques Culex pipiens. 

Liste des publications :

29. C. Braquart-Varnier, M. Raimond, G. Mappa, F. Chevalier, W. Le Clec’h et M. Sicard, 2015. The hematopoietic organ: a cornerstone for Wolbachia propagation between and within hosts. Frontiers in Microbiology 6:1424. doi: 10.3389/fmicb.2015.01424

28. C .Braquart-Varnier*,M. Altinli*, R. Pigeault, F. Chevalier, P. Greve, D. Bouchon et M. Sicard, 2015. The mutualistic side of Wolbachia-Isopod interactions: Wolbachia mediated protection against pathogenic intracellular bacteria. Frontiers in Microbiology 6:1388. doi: 10.3389/fmicb.2015.01388 (*co-first authors)

27. R. Pigeault, C. Braquart-Varnier, I. Marcadé, G Mappa, E. Mottin et M. Sicard* 2014
Modulation of host immunity and reproduction by horizontally acquired Wolbachia. Journal of Insect Physiology 70:125-33.

26. M. Sicard*, J. Dittmer, P. Grève, D. Bouchon et C. Braquart-Varnier, 2014
A host as an ecosystem: Wolbachia coping with environmental constraints. Environmental Microbiology15 (11), 2922–2936

25. M. Sicard, D. Bouchon, L. Ceyrac, R. Raimond, M. Thierry, W. Le Clec’h, I. Marcadé, Y. Caubet et P. Grève* 2014
Bidirectional cytoplasmic incompatibility caused by Wolbachia in the terrestrial isopod Porcellio dilatatus. Journal of Invertebrate Pathology 121 p28-36

24. W. Le Clec’h*, M. Raimond, D. Bouchon et M. Sicard 2014
Strength of the pathogenicity caused by feminizing Wolbachia after transfer in a new host: strain or dose effect? Journal of Invertebrate Pathology 116 p118-126

23. M. Sicard*, M. Raimond , S. Gaudriault, A. Lanois, S. Pagès, C. Debenest, C. Braquart-Varnier et A. Givaudan 2014
Putative toxins from the entomopathogenic bacterium Photorhabdus luminescens kill Armadillidium vulgare (Terrestrial isopod). Biological control 69 p40-44

22.W. Le Clec’h, M. Raimond, S. Guillot, D. Bouchon et M. Sicard* 2013
Horizontal transfers of feminizing versus non feminizing Wolbachia strains: from harmless passengers to pathogens. Environmental Microbiology 15 p2922-2936

21. W. Le Clec’h, F. D. Chevalier, L. Genty, J. Bertaux, D. Bouchon et M. Sicard* 2013 Cannibalism and predation as paths for horizontal passage of Wolbachia between terrestrial isopods. PLoS One(4): e60232. doi:10.1371/journal.pone.0060232

20. W. Le Clec’h, C. Braquart-Varnier, M. Raimond, J-B Ferdy, D. Bouchon et M. Sicard 2012
High virulence of Wolbachia after host switching: When autophagy hurts. PLoS Pathogens 8(8): e1002844. doi:10.1371/journal.ppat.1002844

19. J.Dittmer*, A. Koehler, F-J. Richard, R. Poulin et M. Sicard 2011
Variation of parasite load and immune parameters in two species of New Zealand shore crabs. Parasitology Research 109 p759-767

18. M. Sicard*, F. Chevalier, M. De Vlechouver, D. Bouchon , Pierre Grève et C. Braquart-Varnier 2010
Variations of immune parameters in terrestrial isopods: A matter of gender, age and Wolbachia Naturwissenschaften, 97 p819-826

17. E. Chapuis*, V. Emelianoff, V. Paulmier, N. Le Brun, S. Pagès, M. Sicard et JB. Ferdy 2009
Manifold aspects of specificity in a nematode-bacterium mutualism. Journal of Evolutionary Biology 22 (10) p2104-2117

16. M-M. Lee, M. Sicard et S. P. Stock* 2009
Steinernema boemarei n.sp. (Nematoda: Steinernematidae), a new entomopathogenic nematode from Southern France Systematic Parasitology 72 p127-141

15. C. Braquart-Varnier, M. Lachat, J. Herbinière, M. Johnson, Y. Caubet, D. Bouchon et M. Sicard* 2008
Wolbachia mediate variation of host immunocompetence PLoS One Volume 3 (9)

14. F. Vigneux, F. Bashey*, M. Sicard et C. M. Lively 2008
Low migration decreases interference competition among parasites and increases virulence Journal of Evolutionary Biology 21 p1245-1251

13. M. Sicard*, M. Raimond, O. Prats, A. Lafitte, et C. Braquart-Varnier 2008
Pathogenic effect of entomopathogenic nematode-bacterium complexes on terrestrial isopods Journal of Invertebrate Pathology 99 p20-27

12.V. Emelianoff, N. Le Brun, S. Pagès, P. Stock, P. Tailliez, C. Moulia et M. Sicard* 2008
Isolation and identification of entomopathogenic nematodes and their symbiotic bacteria from Hérault and Gard (Southern France) Journal of Invertebrate Pathology 98 p211-217

11. V. Emelianoff, M. Sicard*, N. Le Brun, C. Moulia et J-B Ferdy 2007
Effect of bacterial symbionts Xenorhabdus on the mortality of infective juveniles of two Steinernema species. Parasitology Research 100 (3) p657-659

10. M. Sicard*, S. Hering, R. Schulte, S. Gaudriault et H. Schulenburg 2007
The effect of Photorhabdus luminescens (Enterobacteriaceae) on the survival, development, reproduction and behaviour of Caenorhabditis elegans (Nematoda: Rhabditidae). Environmental Microbiology 9 (1) p12-25

9. M. Sicard*, J. Hinsinger, N. Le Brun, S. Pagès, N. Boemare et C. Moulia 2006
Interspecific competition between entomopathogenic nematodes (Steinernema) mediated by their bacterial symbionts (Xenorhabdus). BMC Evolutionary Biology 6(1):68

8. M. Sicard*, J. Tabart, B. Godelle, O. Thaler et C. Moulia 2005
Effect of phenotypic variation in Xenorhabdus nematophila onto its mutualistic relationship with the entomopathogenic nematode Steinernema carpocapsae. Parasitology 131p687-694

7. M. Sicard*, H. Ramone, N. Le Brun, S. Pagès et C. Moulia, 2005
Specialization of the entomopathogenic nematode Steinernema scapterisci with its mutualistic Xenorhabdus symbiont. Naturwissenschaften 92 p472-476

6. M. Sicard*, Julie Hinsinger, N. Boemare et C. Moulia 2005
Le Processus de co-évolution au sein de l’interaction symbiotique entre le nématode Steinernema carpocapsae et l’entérobactérie Xenorhabdus nematophila. Bulletin de la Société Française de Zoologie 130 (2): 193-204

5. M. Sicard, K. Brugirard, A. Lanois, N Boemare, M. Bréhelin et A. Givaudan*2004
Stages of infection process during the tripartite interaction between Xenorhabdus nematophila, its nematode vector and insect hosts. Applied and Environmental Microbiology 70 (11) p6473-6480

4. M. Sicard*, J-B. Ferdy, S. Pagès, N. Le Brun, B. Godelle, N. Boemare et C. Moulia 2004 When mutualists are pathogens: an experimental study in the entomopathogenic nematodes (Steinernema)-bacteria (Xenorhabdus) symbioses. Journal of Evolutionary Biology 17 p987-993

3.M. Sicard*, N. Le Brun, S. Pagès, B. Godelle, N. Boemare et C. Moulia 2003
Effect of native Xenorhabdus on the fitness of their Steinernema hosts: contrasting types of interactions. Parasitology Research 91 p520-524

2 M. Sicard*, E. Desmarais et A. Lambert 2002
Is the Octomacridae the sister family of the Diplozoidae ? Parasite, 9 p 85-87

1. M. Sicard*, Desmarais E. et Lambert A. 2001
Caractérisation moléculaire des populations de Diplozoidae sur cinq espèces de Cyprinidae : nouvelles données sur la spécificité parasitaire. CRAS série III life sciences 324 (8) : p 709-717